Image credit: SAR Cosmetic

In both men and women, hair loss is a natural aspect of becoming older. Other factors, such as genetic predispositions, alopecia areata, and even extreme stress, might alter the pace of hair loss. Patients who don’t want surgery can get their hair restored with platelet-rich fibrin (PRF), a cutting-edge technique that is nearly painless. In this article, you’ll learn how PRF hair treatment can help restore bald hair and the differences between PRF and PRP( platelet-rich plasma) treatments. 

What Is PRF Hair Treatment?

PRF hair restoration treatment is a three-step medical procedure that entails injecting concentrated plasma into the scalp to promote hair growth.

PRF, also known as platelet-rich fibrin, is a type of stem cell therapy that employs your own stem cells to induce collagen formation, tissue regeneration, and hair re-growth in the body. Because PRF growth factors are derived from your own blood, the body is more readily accepting of the treatment and natural tissue regeneration is increased. The stimulation of tissue growth causes the growth of hair follicles, which grow larger and healthier as a result, allowing them to create thicker hair. The numerous advantages of PRF hair restoration are enjoyed by both men and women, and they include:

  • Hair thinning.
  • A receding hairline, which is a sign of age.
  • Having a bald head (including small bald spots) 

What Is the Mechanism of Action of PRF for Hair Regrowth?

During a PRF treatment, a patient’s blood is extracted and spun in a centrifuge to remove any harmful elements. By employing the body’s own stem cells to stimulate new hair development and thicken existing hair, this procedure separates platelet-rich fibrin from the rest of the blood and promotes hair growth and thickening. PRF is injected into the area of the scalp where the patient is experiencing hair loss.

What Is the Success Rate of PRF Hair Treatment in Terms of Hair Regrowth?

Patients are often prescribed four treatments to achieve their optimal outcomes, with a maintenance treatment recommended every six to twelve months after the initial series of treatments. Achieving success with this treatment plan is close to 80 percent when it is followed to the letter. PRF is a secure, discrete, and professional service.

Who Is PRF Hair Treatment Meant For?

If you have hair loss and meet the other prerequisites, Dr. Trent may recommend PRF hair restoration. PRF’s growth factors, white blood cells, stem cells, and platelets revive dormant hair follicles. Despite being healthy and able to produce hair, these follicles are becoming dormant. As a result, PRP hair restoration is most effective when the patient experiences early hair loss. Androgenic alopecia is the medical term for this condition.

PRP is effective for both men and women, especially for individuals who are experiencing early-stage hair loss. It’s also helpful for women with traction alopecia, a hair-thinning disorder caused by tight haircuts that limit hair growth. It’s a good option for folks with thinning hair who don’t want to use medicines.

The Procedure for PRF Hair Regrowth

A little amount of blood is extracted, usually about the same amount that would be required for regular laboratory testing. Afterwards, we put the blood into our PRF centrifuge, which runs at reduced speeds in order to maintain the white blood cells and stem cells along with the blood platelets and plasma. After that, the PRF is ready for injection.

After that, your hair will be shampooed, and a topical anesthetic will be put on your skin to ease any pain. We’ll take pictures of the areas that were treated so we can compare them before and after.

PRF will be injected into your scalp in the spots where you are losing hair. These are small injections that are made every half inch or so. We finish by wiping your hair down and calling the treatment a success. You will be able to resume your daily activities or employment immediately.

When Should You Expect Your Hair to Grow?

The objective is twofold. Initially, the hair follicles can’t stay in the “resting” or “dormant” phase of the hair growth cycle for long periods. Second, these follicles need growth factors, stem cells, and platelets in order to come back to life and start growing again.

You’ll notice a significant reduction in hair thinning and loss right away. Following that, you’ll notice noticeable hair growth, which normally occurs within the first two to three months.

The Preparation for PRF Hair Treatment

If you are taking any vitamins or other drugs, Dr. Trent will review them with you. Anti-inflammatory drugs and some supplements will need to be restrained because they could cause bleeding and bruises during the procedure.

Otherwise, it’s a good idea to consume plenty of fluids and stay completely hydrated for the three days leading up to your PRF appointment.

What Does the Aftercare for PRF Hair Treatment Look Like?

There isn’t much hope for a comeback. If you experience any discomfort, you may take an over-the-counter pain reliever, but you should be able to shower and wash your hair right away. Avoid using ice packs on your scalp because the cold can hinder the activity of the PRF. It is possible that your scalp will be slightly pink or red over the treatment regions for several hours following your session. Normal hair care, like blow drying, coloring, curling, and so on, should usually be put off for one to two days.

The Mechanism of Action of PRF Hair Loss Treatment

PRF is 100% natural because it is isolated from the patient’s own blood, hence it has no artificial ingredients. Therefore, it is extremely risk-free, with zero potential for an allergic reaction and a negligible possibility of infection or consequence.

Firstly, “Platelet Rich Fibrin” is an abbreviation for “Platelet Rich Fibrin.” The PRF plasma, often known as “serum,” comprises fibrin, stem cells, white blood cells, and a higher concentration of growth factors than PRP, making it a more effective treatment option. PRF (Platelet Rich Plasma) hair restoration is the next generation of PRP (Platelet Rich Plasma). PRF has more growth factors than PRP, but PRP does not contain fibrin, stem cells, or white blood cells, but PRF does — all of which help to tissue regeneration and are present in higher concentrations in PRF.

In the PRF, “undifferentiated” stem cells are employed to repair follicles and regrow hair. The fibrin in PRF may work as cellular “scaffolding” to keep growth factors and stem cells in the follicle injection region. So, these healing chemicals don’t move away from where they are needed. Because more growth factor is secreted for a longer time, follicles heal more efficiently.

Lastly, when compared to hair restoration surgery, PRF hair loss treatment is far less expensive and significantly less uncomfortable. Furthermore, because it is 100 percent natural, there are no risks associated with surgery and there is no need for a lengthy recuperation period. PRF hair loss treatments also allow your hair to regrow naturally, so no one will ever know you’ve had anything done.

Who Stands to Gain the Most From PRF Hair Treatment?

PRF is most effective in individuals with hair loss patterns that are typical of AGA, as well as in patients who have only recently begun suffering hair loss (within the past five years). Generally speaking, the earlier PRF is initiated, the better the results. It is possible that patients who have been having hair loss for more than five years or who have other types of hair loss can show some improvement in their hair growth after undergoing PRF treatment.

It is possible to experience negative side effects from oral hormone drugs, and topical hormone therapies can be messy and difficult to apply. In addition, some people may not respond to hormone hair loss medicines for a variety of reasons. Therefore, PRF treatments can be an excellent alternative to pharmaceutical treatments.

Patients who are able to tolerate and experience results from hormone hair loss drugs have proven that employing PRF treatments in conjunction with those meds can significantly increase hair growth.*

Potential Dangers and Issues to Consider in PRF Hair Treatment

As a result, PRF therapies are quite safe, in part because the treatment is based on your cells, which means there is a very small danger of complications. During the process itself, there is usually very little or no pain. On the other hand, if you are extremely afraid of needles, numbing agents can be provided on demand. You may experience slight soreness and bruises at the injection sites following the injection procedure. This is very normal and should subside within a week or two of its occurrence. It is critical to inform your doctor about all medications, vitamins, and herbs that you are taking before receiving medical treatment, just as it is with any other medical procedure. It is also vital to inform your doctor of any sensitivities that you may be experiencing.

Is It Possible to Restore Bald Hair With PRF Hair Treatment?

The beauty of platelet-rich fibrin is that it is simply the most homeopathic remedy for hair loss that you could ever hope to find on the market today.

  • The products of your blood are being re-injected into you.
  • As a result, there is no chance that you might have an allergic reaction to it.
  • There are no negative side effects, and the only thing that can happen is that your scalp may feel tight for the first 12 to 24 hours after the procedure.

The Differences Between PRF and PRP Treatments?

Even though platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) have some fundamental similarities, certain critical differences make PRF preferable for hair regrowth in some situations.

  • Both techniques necessitate the drawing of blood, though PRF necessitates less volume. When spinning PRO faster than usual in the centrifuge, stem cells and white blood cells gather in the bottom half of the test tube, while platelets and plasma gather in the top half. The doctor injects platelets and plasma into weakening areas.
  • According to the study, combining more platelets with white blood cells and stem cells is more effective. That is exactly what PRF provides. To make PRF, the blood is spun more than usual, causing the layers to blend together. This allows white blood cells and stem cells to remain in the platelet layer. As a result, PRF contains more healing agents than PRP. Furthermore, the decreased centrifuge speed produces less stress on the individual cells that are being spun.
  • One of the differences between PRP and PRF is the final concentration of platelets in the blood. PRP results in platelet counts that are 2 to 5 times higher than those found in normal blood. PRF contains ten times the platelet concentration of normal blood.
  • PRF contains no chemicals, whereas PRP uses an anticoagulant during processing. In the absence of an anticoagulant, PRF uses fibrinogen, which thrombin converts to fibrin during clot formation. This stimulates the platelets and retains growth factors and stem cells in the injection site, preventing diffusion like PRP.


Platelet-rich fibrin is the most homeopathic remedy for hair loss that you may possibly get. Using your own blood, we’ll be reinjecting it back into you. As a result, an allergic reaction is improbable. After the operation, your scalp may feel tight for 12 to 24 hours.

PRF Hair Treatment FAQs

How long does PRF last for hair loss?

Most patients experience improvement within 6 months of initiating therapy, and many opt for maintenance treatments once or twice yearly after the initial series.

How much does PRF hair treatment cost?

Depending on the desired outcomes, this hair treatment can cost anywhere from $600 to $900.


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